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Effect of necrostatin-1 on sciatic nerve crush injury in rat models

Abstract Background Necrostatin-1 (Nec-1) is an inhibitor of the receptor interacting protein (RIP)1 kinase, which acts as an inhibitor of necroptosis, a special form of necrosis. In the present study, the effect of Nec-1 on peripheral nerve injury (PNI) was investigated. Methods The PNI model was e...

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Detalhes bibliográficos
Principais autores: Chen Yu, Xiaoxu Wang, Jian Qin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-01-01
coleção:Journal of Orthopaedic Surgery and Research
Assuntos:
Acesso em linha:https://doi.org/10.1186/s13018-023-03565-3
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