Neuroprotective effects of Pycnogenol on nerve regeneration and functional recovery after sciatic nerve crush injury in rodents

Abstract Pycnogenol, a standardized French maritime pine bark extract, is known for its antioxidant, anti-inflammatory, and neuroprotective properties. This study evaluated its therapeutic potential in sciatic nerve regeneration following crush injury in female Sprague Dawley rats. Twenty-one rats w...

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Principais autores:	Bhavani R. Nayak, Nanda Acharya, Dhiren Punja, Akash Tomar, Ashwath M. Acharya, Rohini Punja, Nihaal Maripini, Rathi Bishakha Jayprakash
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-10-01
Series:	Scientific Reports
Assuntos:	Pycnogenol Sciatic nerve regeneration Peripheral nerve injury Neuroprotection Sprague Dawley rats Sciatic nerve crush injury
Acceso en liña:	https://doi.org/10.1038/s41598-025-21975-7
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