TET1 mutations as a predictive biomarker for immune checkpoint inhibitors in colon adenocarcinoma
Abstract Background The ten-eleven translocation 1 (TET1), which is essential for active DNA demethylation, plays a multifaceted role in the pathogenesis of colorectal cancer. The study has demonstrated the association of TET1 mutations with a high response to immune checkpoint inhibitors (ICIs) in...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2022-04-01
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| Serie: | World Journal of Surgical Oncology |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12957-022-02581-7 |
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