TET1 mutations as a predictive biomarker for immune checkpoint inhibitors in colon adenocarcinoma

Abstract Background The ten-eleven translocation 1 (TET1), which is essential for active DNA demethylation, plays a multifaceted role in the pathogenesis of colorectal cancer. The study has demonstrated the association of TET1 mutations with a high response to immune checkpoint inhibitors (ICIs) in...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tianzhu Qiu, Xiaoxuan Wang, Furong Du, Xiangjing Hu, Fujun Sun, Chao Song, Jie Zhao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2022-04-01
Schriftenreihe:	World Journal of Surgical Oncology
Schlagworte:	Colon adenocarcinoma Ten-eleven translocation 1 Immune checkpoint inhibitors Overall survival Predictive biomarker
Online-Zugang:	https://doi.org/10.1186/s12957-022-02581-7
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!