SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2

BackgroundPancreatic ductal adenocarcinoma (PDAC) is highly malignant with a poor prognosis, posing significant clinical challenges. SUMOylation, a reversible post-translational modification, plays a critical role in tumor progression, yet its prognostic significance in PDAC remains unclear.MethodsW...

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Autors principals:	Xiangjun Wang, Chuanxin Yang, Yangming Liu, Jian Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-04-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	Pancreatic ductal adenocarcinoma SUMOylation TAK-981 Prognosis SAFB2 Wnt/β-Catenin signaling pathway
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1532658/full
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