SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells

Abstract Background The eukaryotic translation initiation protein eIF5A is a highly conserved and essential factor that plays a critical role in different physiological and pathological processes including stress response and cancer. Different proteomic studies suggest that eIF5A may be a small ubiq...

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Auteurs principaux:	Rocío Seoane, Tomás Lama-Díaz, Antonia María Romero, Ahmed El Motiam, Arantxa Martínez-Férriz, Santiago Vidal, Yanis H. Bouzaher, María Blanquer, Rocío M. Tolosa, Juan Castillo Mewa, Manuel S. Rodríguez, Adolfo García-Sastre, Dimitris Xirodimas, James D. Sutherland, Rosa Barrio, Paula Alepuz, Miguel G. Blanco, Rosa Farràs, Carmen Rivas
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2024-01-01
Collection:	Cellular & Molecular Biology Letters
Sujets:	eIF5A Pancreatic ductal adenocarcinoma Stress granules Stress response SUMO2
Accès en ligne:	https://doi.org/10.1186/s11658-024-00533-5
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