Supramolecular co-assembly of self-adjuvanting nanofibrious peptide hydrogel enhances cancer vaccination by activating MyD88-dependent NF-κB signaling pathway without inflammation

Peptide vaccine targeting tumor-specific antigens is a promising cancer treatment regimen. However, peptide vaccines are commonly low-immunogenic, leading to suboptimal antitumor T-cell responses. Current peptide vaccination approaches are challenged by the variability of peptide physicochemical cha...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Qi Su, Huijuan Song, Pingsheng Huang, Chuangnian Zhang, Jing Yang, Deling Kong, Weiwei Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	KeAi Communications Co., Ltd. 2021-11-01
Schriftenreihe:	Bioactive Materials
Schlagworte:	Cancer immunotherapy Vaccination Peptide Co-assembly Self-adjuvanting
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2452199X21001523
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