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BCAA (Branched-Chain Amino Acids) Inhibiting the Autophagy System via the Activation of mTORC1, Thereby Upregulating the Tumor Suppressor PDCD4 in Huh7 Hepatoma Cells

Branched-chain amino acids (BCAAs) are essential amino acids in humans, with reported anti-proliferative effects on HepG2 hepatoma cells and the potential to reduce hepatocellular carcinoma (HCC) development in cirrhotic patients. PDCD4, a tumor suppressor that is downregulated in many cancers, is a...

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Hlavní autoři: Rasheda Perveen, Iwata Ozaki, Hirokazu Takahashi, Md Manirujjaman, Takuya Kuwashiro, Sachiko Matsuhashi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2025-12-01
Edice:Cells
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On-line přístup:https://www.mdpi.com/2073-4409/14/24/1975
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