Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer

The tumour microenvironment in pancreatic ductal adenocarcinoma (PDA) regulates vascular function and therapeutic response. P21-activated kinases (PAKs) regulate cytoskeletal dynamics and angiogenesis; however, their roles in vascular reprogramming and chemotherapy responses remain unclear. This stu...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Arian Ansardamavandi, Chelsea Dumesny, Sarah Ellis, Ching-Seng Ang, Mehrdad Nikfarjam, Hong He
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2025-11-01
Cyfres:	Cells
Pynciau:	pancreatic ductal adenocarcinoma PAK1 knockdown PAK4 knockout tumour vasculature hypoxia endothelial adhesion molecules
Mynediad Ar-lein:	https://www.mdpi.com/2073-4409/14/22/1806
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!