Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects

The naturally occurring isothiocyanate sulforaphane, found in <i>Brassicaceae</i> vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven sulforaphane analogues by substitution of the sulfinyl...

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Библиографические подробности

Главные авторы:	Christina Georgikou, Laura Buglioni, Maximilian Bremerich, Nico Roubicek, Libo Yin, Wolfgang Gross, Carsten Sticht, Carsten Bolm, Ingrid Herr
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2020-05-01
Серии:	Biomolecules
Предметы:	bioactive agents drug development microRNA signaling pancreatic cancer NCI-60 sulforaphane
Online-ссылка:	https://www.mdpi.com/2218-273X/10/5/769
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