Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

Abstract Background How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. Methods The miRNA levels were detected by qRT-PCR. Protein...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xiaolan Zhu, Huiling Shen, Xinming Yin, Meiling Yang, Hong Wei, Qi Chen, Fan Feng, Yueqin Liu, Wenlin Xu, Yuefeng Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-02-01
Цуврал:	Journal of Experimental & Clinical Cancer Research
Нөхцлүүд:	Exosome miR-223 Chemoresistance Macrophages EOC
Онлайн хандалт:	http://link.springer.com/article/10.1186/s13046-019-1095-1
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!