PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease

ABSTRACT The poly(ADP‐ribose) polymerase (PARP) family consists of 17 members of nicotinamide adenine dinucleotide (NAD⁺)‐dependent enzymes that regulate key biological processes by catalyzing adenosine diphosphate (ADP)‐ribosylation, either poly(ADP‐ribosyl)ation (PARylation) or mono(ADP‐ribosyl)at...

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Autors principals:	Pengyuan Lei, Wenfeng Li, Jinhua Luo, Nanxin Xu, Yahe Wang, Dafei Xie, Hua Guan, Bo Huang, Xin Huang, Pingkun Zhou
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-09-01
Col·lecció:	MedComm
Matèries:	PARP family physiological functions pathological mechanisms DNA damage repair metabolic regulation PARP‐targeted therapy
Accés en línia:	https://doi.org/10.1002/mco2.70314
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