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PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease

ABSTRACT The poly(ADP‐ribose) polymerase (PARP) family consists of 17 members of nicotinamide adenine dinucleotide (NAD⁺)‐dependent enzymes that regulate key biological processes by catalyzing adenosine diphosphate (ADP)‐ribosylation, either poly(ADP‐ribosyl)ation (PARylation) or mono(ADP‐ribosyl)at...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Pengyuan Lei, Wenfeng Li, Jinhua Luo, Nanxin Xu, Yahe Wang, Dafei Xie, Hua Guan, Bo Huang, Xin Huang, Pingkun Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2025-09-01
Schriftenreihe:MedComm
Schlagworte:
PARP family
physiological functions
pathological mechanisms
DNA damage repair
metabolic regulation
PARP‐targeted therapy
Online-Zugang:https://doi.org/10.1002/mco2.70314
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