Pancreatic melatonin enhances anti-tumor immunity in pancreatic adenocarcinoma through regulating tumor-associated neutrophils infiltration and NETosis

Tumor microenvironment contributes to poor prognosis of pancreatic adenocarcinoma (PAAD) patients. Proper regulation could improve survival. Melatonin is an endogenous hormone that delivers multiple bioactivities. Here we showed that pancreatic melatonin level is associated with patients' survival....

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yau-tuen Chan, Hor-yue Tan, Yuanjun Lu, Cheng Zhang, Chien-shan Cheng, Junyu Wu, Ning Wang, Yibin Feng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-04-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Pancreatic adenocarcinoma Melatonin Anti-tumor immunity Tumor-associated neutrophils Tumor microenvironment CXCL2
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383523000229
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!