Molecular architecture of the human tRNA ligase complex

RtcB enzymes are RNA ligases that play essential roles in tRNA splicing, unfolded protein response, and RNA repair. In metazoa, RtcB functions as part of a five-subunit tRNA ligase complex (tRNA-LC) along with Ddx1, Cgi-99, Fam98B, and Ashwin. The human tRNA-LC or its individual subunits have been i...

詳細記述

書誌詳細

主要な著者:	Alena Kroupova, Fabian Ackle, Igor Asanović, Stefan Weitzer, Franziska M Boneberg, Marco Faini, Alexander Leitner, Alessia Chui, Ruedi Aebersold, Javier Martinez, Martin Jinek
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2021-12-01
シリーズ:	eLife
主題:	tRNA splicing ligase unfolded protein response helicase x-ray crystallography
オンライン･アクセス:	https://elifesciences.org/articles/71656
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