Impact of CDK Inhibitors on <i>TBXT</i> Expression in Chordoma Cell Lines Including the First Stable Cell Line of a High-Grade Chordoma

Chordomas are very rare malignant neoplasms of the bone occurring almost exclusively along the spine. As the tumours are thought to arise from notochordal remnants, the vast majority of chordomas express the <i>TBXT</i> gene, resulting in detectable nuclear amounts of its gene product brachyury. Thi...

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Autori principali:	Sarah Bette, Luisa Haase, Juliane Nell, Thomas Grieser, Alexandra von Baer, Markus Schultheiss, Ralf Marienfeld, Peter Möller, Thomas F. E. Barth, Kevin Mellert
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-05-01
Serie:	Diagnostics
Soggetti:	chordoma brachyury dinaciclib THZ1 cell line
Accesso online:	https://www.mdpi.com/2075-4418/14/10/1028
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