Predicting gene expression changes from chromatin structure modification
Abstract Spatial organization of chromatin plays a critical role in gene transcription, but connecting population-averaged HiC data to functional outcomes remains a challenge. We present a computational framework linking HiC contact map to gene transcription. Utilizing a bead-spring polymer model in...
Spremljeno u:
| Glavni autori: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2025-04-01
|
| Serija: | npj Systems Biology and Applications |
| Online pristup: | https://doi.org/10.1038/s41540-025-00510-4 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|