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MCC950 Targeted Inhibition of TXNIP-NLRP3 Axis-mediated Podocyte Pyroptosis in Diabetic Nephropathy

Diabetic Nephropathy (DN) is the leading cause of end-stage renal disease (ESRD) globally, representing a major global health burden with limited disease-modifying therapies. Podocyte injury serves as the core pathological hallmark of DN, and conventional treatments targeting metabolic disorders or...

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Bibliografische Detailangaben
Hauptverfasser: ZHENG Hong, MO Zhong-Cheng, LIU Hang, PAN Xi-Zhang, WEI Bing
Format: Artigo
Sprache:Chinês
Veröffentlicht: Editorial Office of Progress in Biochemistry and Biophysics 2026-02-01
Schriftenreihe:Shengwu huaxue yu shengwu wuli jinzhan
Schlagworte:
Online-Zugang:https://www.pibb.ac.cn/pibbcn/article/abstract/20250382
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