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MCC950 Targeted Inhibition of TXNIP-NLRP3 Axis-mediated Podocyte Pyroptosis in Diabetic Nephropathy

Diabetic Nephropathy (DN) is the leading cause of end-stage renal disease (ESRD) globally, representing a major global health burden with limited disease-modifying therapies. Podocyte injury serves as the core pathological hallmark of DN, and conventional treatments targeting metabolic disorders or...

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Principais autores: ZHENG Hong, MO Zhong-Cheng, LIU Hang, PAN Xi-Zhang, WEI Bing
Formato: Artigo
Idioma:Chinês
Publicado em: Editorial Office of Progress in Biochemistry and Biophysics 2026-02-01
coleção:Shengwu huaxue yu shengwu wuli jinzhan
Assuntos:
Acesso em linha:https://www.pibb.ac.cn/pibbcn/article/abstract/20250382
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