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Dimethyl malonate alleviates obstructive nephropathy by enhancing renal metabolism and inhibiting kidney oxidative stress and inflammation

IntroductionObstructive nephropathy is a leading cause of renal injury and fibrosis. Mitochondrial dysfunction represents a hallmark of obstructive nephropathy, a condition that leads to metabolic aberrations, succinate accumulation, reactive oxygen species (ROS) overproduction, tubular damage, and...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wei Zhang, Changde Fu, Jinjin Lai, Jun Xin, Wenbin Zhang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2025-06-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2025.1530635/full
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