Redoxhigh phenotype mediated by KEAP1/STK11/SMARCA4/NRF2 mutations diminishes tissue-resident memory CD8+ T cells and attenuates the efficacy of immunotherapy in lung adenocarcinoma

Metabolism reprogramming within the tumor microenvironment (TME) can have a profound impact on immune cells. Identifying the association between metabolic phenotypes and immune cells in lung adenocarcinoma (LUAD) may reveal mechanisms of resistance to immune checkpoint inhibitors (ICIs). Metabolic p...

Descripció completa

Dades bibliogràfiques

Autors principals:	Xue-Wu Wei, Chang Lu, Yi-Chen Zhang, Xue Fan, Chong-Rui Xu, Zhi-Hong Chen, Fen Wang, Xiao-Rong Yang, Jia-Yi Deng, Ming-Yi Yang, Qing Gou, Shi-Qi Mei, Wei-Chi Luo, Ri-Wei Zhong, Wen-Zhao Zhong, Jin-Ji Yang, Xu-Chao Zhang, Hai-Yan Tu, Yi-Long Wu, Qing Zhou
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2024-12-01
Col·lecció:	OncoImmunology
Matèries:	Immune checkpoint inhibitors KEAP1/STK11/SMARCA4/NRF2 mutations lung adenocarcinoma metabolic phenotypes tissue-resident memory CD8+ T cells
Accés en línia:	https://www.tandfonline.com/doi/10.1080/2162402X.2024.2340154
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!