Kinetically activating nanovaccine mimicking multidimensional immunomodulation of natural infection for broad protection against heterologous viruses in animal models

Abstract Immunity by vaccination can protect human against heterologous viruses. However, protective abilities of artificial vaccines are still weaker than natural infections. Here we develop a kinetically engineered vaccine (KE-VAC) that mimics the multidimensional immunomodulation in natural infec...

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Detalhes bibliográficos

Principais autores:	Sang Nam Lee, Young-Il Kim, Jaemoo Kim, D. K. Haluwana, Ryounho Eun, Sei Hyun Park, Janghun Heo, Juryeon Gil, Yebin Seong, Min-Ho Lee, Young-Woock Noh, Jong-Soo Lee, Young Ki Choi, Yong Taik Lim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-03-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-025-58006-y
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