A polymer nanogel-based therapeutic nanovaccine for prophylaxis and direct treatment of tumors via a full-cycle immunomodulation

Construction of a cancer nanovaccine that can simultaneously activate immune cells and exert efficient tumor treatment still remains a challenge. Herein, we showcase a proof-of-concept demonstration of an advanced therapeutic nanovaccine formulation based on poly(N-vinylcaprolactam) nanogels (NGs) w...

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Detalhes bibliográficos

Principais autores:	Yunqi Guo, Zhiqiang Wang, Gaoming Li, Mengsi Zhan, Tingting Xiao, Jianhong Wang, Jan C.M. van Hest, Xiangyang Shi, Mingwu Shen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2025-01-01
coleção:	Bioactive Materials
Assuntos:	PVCL nanogels Apoptotic cancer cell membranes Therapeutic nanovaccine STING activation Direct therapy-assisted full-cycle immunomodulation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452199X24004195
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