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Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

The inability of neutrophils to eradicate Pseudomonas aeruginosa within the cystic fibrosis (CF) airway eventually results in chronic infection by the bacteria in nearly 80 percent of patients. Phagocytic killing of P. aeruginosa by CF neutrophils is impaired due to decreased cystic fibrosis transme...

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Detalles Bibliográficos
Principais autores: Robert L Young, Kenneth C Malcolm, Jennifer E Kret, Silvia M Caceres, Katie R Poch, David P Nichols, Jennifer L Taylor-Cousar, Milene T Saavedra, Scott H Randell, Michael L Vasil, Jane L Burns, Samuel M Moskowitz, Jerry A Nick
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3164657?pdf=render
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