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Diffusion MRI marks progressive alterations in fiber integrity in the zQ175DN mouse model of Huntington's disease

Huntington's disease (HD) is a progressive neurodegenerative disease affecting motor and cognitive abilities. Multiple studies have found white matter anomalies in HD-affected humans and animal models of HD. The identification of sensitive white-matter-based biomarkers in HD animal models will be im...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Nicholas Vidas-Guscic, Joëlle van Rijswijk, Johan Van Audekerke, Ben Jeurissen, Israel Nnah, Haiying Tang, Ignacio Muñoz-Sanjuan, Dorian Pustina, Roger Cachope, Annemie Van der Linden, Daniele Bertoglio, Marleen Verhoye
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2024-04-01
Rangatū:Neurobiology of Disease
Ngā marau:
Fixel-based analysis
Neurodegeneration
Huntington's disease
Longitudinal
Preclinical
Neurofilament
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S0969996124000378
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