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Bacterial endotoxins: biological properties and mechanisms of action

Endotoxins (lipopolysaccharides, LPS) are agents of pathogenicity of Gram-negative bacteria, implicated in the development of Gram-negative shock. Endotoxin reacts with lipopolysaccharide-sensitive cells producing endogenous mediators such as tumour necrosis factor alpha (TNFα). Macrophages are cell...

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Bibliografiske detaljer
Principais autores: C. Galanos, M. A. Freudenberg
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 1993-01-01
Serier:Mediators of Inflammation
Online adgang:http://dx.doi.org/10.1155/S0962935193000687
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