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Characterization of Sex-Based Differences in Gut Microbiota That Correlate with Suppression of Lupus in Female BWF1 Mice

Systemic lupus erythematosus (SLE) is more prevalent in female mice and humans and is associated with microbiota dysbiosis. We analyzed the fecal microbiota composition in female and male NZBxNZWF1 (BWF1) mice, a model of SLE, using 16S RNA gene sequencing. Composition of gut microbiota differed bet...

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Principais autores: James W. Harder, Jing Ma, James Collins, Pascale Alard, Venkatakrishna R. Jala, Haribabu Bodduluri, Michele M. Kosiewicz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-04-01
coleção:Microorganisms
Assuntos:
autoimmune disease
systemic lupus erythematosus
gut microbiota
sex
fecal transplant
therapy
Acesso em linha:https://www.mdpi.com/2076-2607/13/5/1023
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