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Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Abstract Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex etiology involving both innate and adaptive immune dysregulation. Among several perturbed signaling pathways, decreased ERK activity in CD4⁺ T-cells has been linked to DNA hypomethylation and aberrant gene exp...

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Bibliografiset tiedot
Päätekijät: M. L. Eloranta, P. Nygren, R. Larsson, A. Loskog, N. Woodworth, M. Hultqvist, Richard Svensson, Ylva Gravenfors, L. Rönnblom, Mårten Fryknäs
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2026-02-01
Sarja:Scientific Reports
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Linkit:https://doi.org/10.1038/s41598-026-37930-z
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