Whole exome sequencing reveals a C-terminal germline variant in CEBPA-associated acute myeloid leukemia: 45-year follow up of a large family

Familial acute myeloid leukemia is rare and linked to germline mutations in RUNX1, GATA2 or CCAAT/enhancer binding protein-α (CEBPA). We re-evaluated a large family with acute myeloid leukemia originally seen at NIH in 1969. We used whole exome sequencing to study this family, and conducted in silic...

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Автори:	Anand Pathak, Katja Seipel, Alexander Pemov, Ramita Dewan, Christina Brown, Sarangan Ravichandran, Brian T. Luke, Michael Malasky, Shalabh Suman, Meredith Yeager, NCI DCEG Cancer Genomics Research Laboratory, NCI DCEG Cancer Sequencing Working Group, Richard A. Gatti, Neil E. Caporaso, John J. Mulvihill, Lynn R. Goldin, Thomas Pabst, Mary L. McMaster, Douglas R. Stewart
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Ferrata Storti Foundation 2016-07-01
Серія:	Haematologica
Онлайн доступ:	https://haematologica.org/article/view/7771
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