A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids
Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate. Here we describe a new rapid and efficient approach for the synthesis of click-based...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020-05-01
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| Schriftenreihe: | Frontiers in Chemistry |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/article/10.3389/fchem.2020.00405/full |
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