The Mitochondrial PHB Complex Determines Lipid Composition and Interacts With the Endoplasmic Reticulum to Regulate Ageing

Metabolic disorders are frequently associated with physiological changes that occur during ageing. The mitochondrial prohibitin complex (PHB) is an evolutionary conserved context-dependent modulator of longevity, which has been linked to alterations in lipid metabolism but which biochemical function...

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Autors principals:	Artur B. Lourenço, María Jesús Rodríguez-Palero, Mary K. Doherty, David Cabrerizo Granados, Blanca Hernando-Rodríguez, Joaquín J. Salas, Mónica Venegas-Calerón, Phillip D. Whitfield, Marta Artal-Sanz
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-07-01
Col·lecció:	Frontiers in Physiology
Matèries:	mitochondria prohibitin (PHB) insulin ageing lipidomics yolk
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphys.2021.696275/full
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