The Mitochondrial PHB Complex Determines Lipid Composition and Interacts With the Endoplasmic Reticulum to Regulate Ageing

Metabolic disorders are frequently associated with physiological changes that occur during ageing. The mitochondrial prohibitin complex (PHB) is an evolutionary conserved context-dependent modulator of longevity, which has been linked to alterations in lipid metabolism but which biochemical function...

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Principais autores:	Artur B. Lourenço, María Jesús Rodríguez-Palero, Mary K. Doherty, David Cabrerizo Granados, Blanca Hernando-Rodríguez, Joaquín J. Salas, Mónica Venegas-Calerón, Phillip D. Whitfield, Marta Artal-Sanz
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2021-07-01
叢編:	Frontiers in Physiology
主題:	mitochondria prohibitin (PHB) insulin ageing lipidomics yolk
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fphys.2021.696275/full
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