Modulation of NF-κB and cytokine signaling by Cordia dichotoma and Cordia myxa attenuates methotrexate-induced pulmonary inflammation and oxidative injury in rats

BackgroundMethotrexate (MTX) is a widely used anticancer and immunosuppressive agent, but its clinical use is limited by lung injury associated with oxidative stress, inflammation, and fibrosis. Leaves of Cordia dichotoma and Cordia myxa traditionally have been used for respiratory disorders, sugges...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Nermine M. Mohammed, Hoda M. Hassan, Fatma A. Moharram, Elsayed K. El-Sayed, Asmaa A. Ahmed, Mohamad Elbaz, Merhan E. Ali, Chia-Ying Lin, Kuei-Hung Lai, Shahenda Mahgoub, Hanan G. Sary, Heba T. Khazaal
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2026-06-01
Sarja:	Frontiers in Pharmacology
Aiheet:	Cordia dichotoma Cordia myxa lung inflammation methotrexate oxidative stress TGF-β1/α-SMA signaling
Linkit:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1836019/full
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