Mycobacterium tuberculosis VadK is required for the regulation of the methylcitrate cycle and virulence
Abstract The evolution of new enzymatic functions is constrained and guided by the architecture of an organism’s metabolic and regulatory networks and environmental constraints. Here, we identify a kinase that has evolved from pyruvate phosphate dikinase. Using biochemical and systems-level analyses...
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| Автори: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Springer Nature
2026-06-01
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| Серія: | EMBO Reports |
| Онлайн доступ: | https://doi.org/10.1038/s44319-026-00818-0 |
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