AMP‐activated protein kinase inhibition in fibro‐adipogenic progenitors impairs muscle regeneration and increases fibrosis

Abstract Background Following muscle injury, fibro‐adipogenic progenitors (FAPs) are rapidly activated and undergo apoptosis at the resolution stage, which is required for proper muscle regeneration. When excessive FAPs remain, it contributes to fibrotic and fatty infiltration, impairing muscle reco...

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Autores principales:	Xiangdong Liu, Liang Zhao, Yao Gao, Yanting Chen, Qiyu Tian, Jun Seok Son, Song Ah Chae, Jeanene Marie deAvila, Mei‐Jun Zhu, Min Du
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-02-01
Colección:	Journal of Cachexia, Sarcopenia and Muscle
Materias:	AMPK FAPs fibrosis MMP‐9 obesity TGF‐β
Acceso en línea:	https://doi.org/10.1002/jcsm.13150
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!