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Advances, limitations and perspectives in the use of celecoxib-loaded nanocarriers in therapeutics of cancer

Abstract Cancer is highlighted as a major global health challenge in the XXI century. The cyclooxygenase-2 (COX-2) enzyme rises as a widespread tumor progression marker. Celecoxib (CXB) is a selective COX-2 inhibitor used in adjuvant cancer therapy, but high concentrations are required in humans. In...

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Principais autores: Miguel de Jesus Oliveira Santos, Jéssica Teles-Souza, Renata Freitas de Araújo-Calumby, Robert L. Copeland, Henrique Rodrigues Marcelino, Deise Souza Vilas-Bôas
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2024-09-01
Serier:Discover Nano
Fag:
Cancer
COX-2
Celecoxib
Nanocarriers
Nanoparticles
Drug delivery systems
Online adgang:https://doi.org/10.1186/s11671-024-04070-0
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