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Preparation and Characterization of Celecoxib-Conjugated Polyethylenimine as a Potential Nanocarrier for Gene Delivery

The objective of the present investigation was to conjugate celecoxib as a cyclooxygenase-2 (COX-2) inhibitor onto polyethylenimine (PEI) in order to prepare nanoparticles for tissue targeting. Since celecoxib binds to COX-2 and this enzyme is over expressed in several pathological conditions includ...

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Бібліографічні деталі
Автори: Hossein Sadeghpour, Kobra Roshan Nasrabad, Marjan Alipour Haghighi, Ali Dehshahri
Формат: Artigo
Мова:Inglês
Опубліковано: Shiraz University of Medical Sciences 2018-03-01
Серія:Trends in Pharmaceutical Sciences
Предмети:
Онлайн доступ:http://tips.sums.ac.ir/article_42246_6e9aebdcfa921c81dcaa0917f4452086.pdf
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