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Trans unsaturated fatty acids inhibit lecithin: cholesterol acyltransferase and alter its positional specificity1

Although dietary trans unsaturated fatty acids (TUFA) are known to decrease plasma HDL, the underlying mechanisms for this effect are unclear. We tested the hypothesis that the decreased HDL is due to an inhibition of lecithin:cholesterol acyltransferase (LCAT), the enzyme essential for the formatio...

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Principais autores: Papasani V. Subbaiah, Veedamali S. Subramanian, Ming Liu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 1998-07-01
Serier:Journal of Lipid Research
Fag:
high density lipoproteins
LCAT
cholesterol esterification
fluidity
acyl chain length
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520325256
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