Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation

Glioblastoma (GBM), an aggressive brain malignancy with a cellular hierarchy dominated by GBM stem cells (GSCs), evades antitumor immunity through mechanisms that remain incompletely understood. Like most cancers, GBMs undergo metabolic reprogramming toward glycolysis to generate lactate. Here, we s...

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מידע ביבליוגרפי

Principais autores:	Shuai Wang, Tengfei Huang, Qiulian Wu, Huairui Yuan, Xujia Wu, Fanen Yuan, Tingting Duan, Suchet Taori, Yingming Zhao, Nathaniel W. Snyder, Dimitris G. Placantonakis, Jeremy N. Rich
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical Investigation 2024-11-01
סדרה:	The Journal of Clinical Investigation
נושאים:	Metabolism Oncology
גישה מקוונת:	https://doi.org/10.1172/JCI176851
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!