Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice

BackgroundThe origin of intervertebral disc degeneration (IDD) is highly complex, where both cartilage endplate remodeling and vertebral osteoporosis are of utmost importance. Myristic acid (MA), a saturated fatty acid derived from nutmeg, a traditional Chinese herb, has been shown to boost memory....

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Bibliografische Detailangaben

Hauptverfasser:	Yan Gong, Yuzhuo Zhang, Xingda Chen, Zelin Zhou, Weicheng Qin, Yanchi Gan, Jiahui He, Jizhi Ma, Guifeng Chen, Qi Shang, Kai Tang, Honglin Chen, Yu Liu, De Liang, Gengyang Shen, Xiaobing Jiang, Zhaojun Cheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-04-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	myristic acid endplate chondrocytes osteoporosis endplate osteochondral remodeling intervertebral disc degeneration
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1517221/full
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