Dual-utility ctDNA in diffuse large B-cell lymphoma: integrated genotyping unveils minimal residual disease dynamics and subtype-specific clonal evolution

Abstract Background Circulating tumor DNA (ctDNA) profiling offers a noninvasive approach to monitor minimal residual disease (MRD) and clonal evolution in diffuse large B-cell lymphoma (DLBCL). Methods In this study, we analyzed 164 newly diagnosed DLBCL patients from the First Affiliated Hospital...

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Autors principals:	Jin-Hua Liang, Yi-Fan Wu, Si-Ying Pan, Kai-Xin Du, Yi-Lun Ji, Liu-Qing Zhu, Hao-Rui Shen, Jia-Zhu Wu, Hua Yin, Yue Li, Li Wang, Jian-Yong Li, Wei Xu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-03-01
Col·lecció:	BMC Medicine
Matèries:	Diffuse large B-cell lymphoma Circulating tumor DNA Minimal residue disease Clonal evolution
Accés en línia:	https://doi.org/10.1186/s12916-026-04756-5
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