Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.

BACKGROUND: Technologies based on DNA microarrays have the potential to provide detailed information on genomic aberrations in tumor cells. In practice a major obstacle for quantitative detection of aberrations is the heterogeneity of clinical tumor tissue. Since tumor tissue invariably contains gen...

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Detalhes bibliográficos

Principais autores:	Hanna Göransson, Karolina Edlund, Maria Rydåker, Markus Rasmussen, Johan Winquist, Simon Ekman, Michael Bergqvist, Andrew Thomas, Mats Lambe, Richard Rosenquist, Lars Holmberg, Patrick Micke, Johan Botling, Anders Isaksson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2009-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC2699026?pdf=render
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