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<it>KRAS </it>analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

<p>Abstract</p> <p>Background</p> <p>Epidermal growth factor receptor inhibitor therapy is now approved for treatment of metastatic colorectal carcinomas (CRC) in patients with tumors lacking <it>KRAS </it>mutations. Several procedures to detect <it>KRAS </it>mutations have been developed. However,...

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Hlavní autoři: Birgisson Helgi, Glimelius Bengt, Lindell Monica, Edlund Karolina, Sundström Magnus, Micke Patrick, Botling Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2010-12-01
Edice:BMC Cancer
On-line přístup:http://www.biomedcentral.com/1471-2407/10/660
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