PERsonalised Medicine for Intensification of Treatment (PERMIT) in type 2 diabetes mellitus: a target trial emulation from routine data

Background Evidence is required on the relative effectiveness of sulphonylureas, dipeptidyl peptidase-4 inhibitors or sodium–glucose cotransporter 2 inhibitors added to metformin for people with type 2 diabetes mellitus. Objectives To assess disparities in the initiation of second-line antidiabetic...

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Detalhes bibliográficos

Principais autores:	David G Lugo-Palacios, Patrick Bidulka, Paul Charlton, Bill Huston, Anna Carnegie, Orlagh Carroll, Stephen O’Neill, Amanda I Adler, Anirban Basu, Richard J Silverwood, Andrew H Briggs, Liam Smeeth, Ian J Douglas, Kamlesh Khunti, Richard Grieve
Formato:	Artigo
Idioma:	Inglês
Publicado em:	NIHR Journals Library 2026-06-01
coleção:	Health Technology Assessment
Assuntos:	type 2 diabetes mellitus comparative effectiveness electronic health records heterogenous treatment effects multiple long-term conditions target trial emulation instrumental variables microsimulation
Acesso em linha:	https://doi.org/10.3310/ASDB8011
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