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Engineering mRNA-LNP therapeutics: Nanomaterials for preservation, controlled release, and inhalation delivery

Messenger RNA (mRNA) therapeutics are rapidly becoming a paradigm-shifting technology in the fields of vaccines and gene therapy. Nevertheless, the scalability and translatability of mRNA vaccines and therapeutics are currently hampered by the inherent physicochemical instability of mRNA-lipid nanop...

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Principais autores: Muhammad Imad Khan Khalil, Muhammad Kamran Khan, Muhammad Noman Noor, Jingyu Shi, Imam Hussain, Ijaz Ahmad, Shaukat Aziz, Tong Zhenbo, Hongtao Xu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-07-01
Serier:Next Materials
Fag:
mRNA-LNP
Nanoparticles
Vaccines
Cryopreservation
Freeze-drying
Aerosolization
Online adgang:http://www.sciencedirect.com/science/article/pii/S2949822826007926
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