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Resistance Mechanisms to BCMA Targeting Bispecific Antibodies and CAR T-Cell Therapies in Multiple Myeloma

B-cell maturation antigen (BCMA)-targeted therapies including both chimeric antigen receptor (CAR) T-cell therapies and bispecific antibodies (BsAbs), have revolutionized the treatment landscape for relapsed/refractory multiple myeloma (MM), offering both deep and durable responses, even in heavily...

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Principais autores: Brandon Tedder, Manisha Bhutani
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-07-01
Serier:Cells
Fag:
BCMA
multiple myeloma
bispecific antibodies
CAR-T cell therapies
tumor microenvironment
antigen escape
Online adgang:https://www.mdpi.com/2073-4409/14/14/1077
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