Key predictors of long-term outcomes in BCMA-targeted CAR-T therapy for relapsed/refractory multiple myeloma

Abstract Background B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell (CAR-T) therapy exhibits high response rates in patients with relapsed/refractory multiple myeloma (r/r MM). However, the specific factors that influence the response duration remain poorly understood. Met...

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Autori principali:	Ning An, Juan Li, Pan Luo, Di Wang, Peiling Zhang, Chang Shu, Songbai Cai, Qiuxia Yu, Xinyu Wen, Xinran Wang, Wei Mu, Jianlin Hu, Chunrui Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-05-01
Serie:	Journal of Translational Medicine
Soggetti:	R/R multiple myeloma BCMA CAR-T MRD CAR-T cell
Accesso online:	https://doi.org/10.1186/s12967-025-06543-x
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