Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

Summary: To explore mechanisms of response to combined PD-1/CTLA-4 immune checkpoint blockade (ICB) treatment in individual cell types, we generated scRNA-seq using a mouse model of invasive urothelial carcinoma with three conditions: untreated tumor, treated tumor, and tumor treated after CD4+ T ce...

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主要な著者:	Sharon L. Freshour, Timothy H.-P. Chen, Bryan Fisk, Haolin Shen, Matthew Mosior, Zachary L. Skidmore, Catrina Fronick, Jennifer K. Bolzenius, Obi L. Griffith, Vivek K. Arora, Malachi Griffith
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2023-10-01
シリーズ:	iScience
主題:	Oncology Immunology Transcriptomics
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S258900422302014X
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