Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer

Summary: Although tobacco use is an independent adverse prognostic feature in HPV(+) oropharyngeal squamous cell carcinoma (OPSCC), the biologic features associated with tobacco use have not been systematically investigated. We characterized genomic and immunologic features associated with tobacco u...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Benjamin M. Wahle, Paul Zolkind, Ricardo J. Ramirez, Zachary L. Skidmore, Sydney R. Anderson, Angela Mazul, D. Neil Hayes, Vlad C. Sandulache, Wade L. Thorstad, Douglas Adkins, Obi L. Griffith, Malachi Griffith, Jose P. Zevallos
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2022-05-01
Σειρά:	iScience
Θέματα:	Oncology Immunology Genomics
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2589004222004862
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