Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Sarco/endoplasmic reticulum Ca²⁺ ATPase (SERCA) is a crucial component of the cellular machinery responsible for Ca²⁺ homeostasis. The selective inhibition of SERCA by thapsigargin (TG) leads to perturbations in Ca²⁺ signaling, which can trigger endoplasmic reticulum...

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Principais autores:	Ana Catarina Pereira, Nuno Madeira, Sofia Morais, António Macedo, Maria Teresa Cruz, Cláudia M. F. Pereira
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-01-01
Series:	Cells
Assuntos:	calcium homeostasis endoplasmic reticulum (ER) stress immune system sterile inflammation mitochondria dynamics
Acceso en liña:	https://www.mdpi.com/2073-4409/11/3/433
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